Package index • cosmicsig

Package

cosmicsig cosmicsig-package: cosmicsig: A package of mutational signatures from COSMIC (Catalogue Of Somatic Mutations In Cancer) https://cancer.sanger.ac.uk/signatures/.

Signature data (latest release)

signature: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.5 - November 2025)

Per-release signature snapshots

COSMIC_v3.0: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.0 - May 2019)
COSMIC_v3.1: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.1 - June 2020)
COSMIC_v3.2: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.2 - March 2021)
COSMIC_v3.3: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.3 - June 2022)
COSMIC_v3.4: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.4 - October 2023)
COSMIC_v3.5: Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.5 - November 2025)

Helpers

SBS96_ID_to_SBS192_ID(): Translate SBS96 signature IDs to SBS192 signature IDs by adding "-E" if necessary
possible_artifacts(): Return a character vector of the names of possible signature artifacts
rare_signatures(): Return a character vector of the names of rare SBS96 signatures

Deprecated

These are no longer maintained and may be incomplete for recent COSMIC releases. For authoritative, up-to-date etiologies consult https://cancer.sanger.ac.uk/signatures/ directly.

etiology: List of mutational signatures' proposed etiology summarized from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.5 - November 2025)
get_etiology(): Get the proposed etiology of mutational signatures.