Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.5 - November 2025)

Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.5 - November 2025)

Usage

COSMIC_v3.5

Format

A list with two elements, signature and etiology.

• signature is a list with the same structure as signature.

• etiology is a list with the same structure as etiology. The etiology information is deprecated and is no longer being updated. It is not versioned at the COSMIC website and may not reflect signatures added in recent COSMIC releases. For authoritative, up-to-date etiologies consult https://cancer.sanger.ac.uk/signatures/ directly.

Source

https://cancer.sanger.ac.uk/signatures/.

Remark

The signatures are all genome signatures. See https://cancer.sanger.ac.uk/signatures/.

Examples

sbs96_sig_v3.5 <- COSMIC_v3.5$signature$GRCh37$SBS96